BDBM25284 (1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phenyl]phenyl}-1-phosphonoethyl)phosphonic acid::BPH-675::bisphosphonate, 6

SMILES OC(Cc1cccc(c1)-c1cccc(NS(=O)(=O)c2ccc3ccccc3c2)c1)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=MZVWVRVNMXTDAK-UHFFFAOYSA-N

Data  2 KI  4 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25284   

TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego

LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)
Affinity DataIC50:  8.20E+3nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed